Acanthosis nigricans orsak

Understanding Acanthosis Nigricans: Causes, Symptoms, and Treatment

Acanthosis nigricans fryst vatten a skin condition that is often associated with metabolic disorders such as diabetes, obesity, and insulin resistance. While this condition affects both males and females, it is most common in individuals of African American descent. Understanding the causes, symptoms, and treatment of acanthosis nigricans can help individuals recognize and manage this condition in an effective manner.

What is Acanthosis Nigricans?

Acanthosis nigricans is a skin disorder characterized bygd thick, dark, and velvety patches that typically develop on the back of the neck, groin, and underarms. The affected area may also feel itchy or rough to the touch. In rare cases, acanthosis nigricans can occur in the lips, palms, and soles of the feet.

Definition and Overview

Acanthosis nigricans is a medical begrepp used to describe areas of thick, dark skin that may appear in people who are overweight, diabetic, or have an underlying medical condition. While it fryst vatten not painful or contagious, it can be a sign of an underlying health problem.

Prevalence and Demographics

Acanthosis nigricans fryst vatten more prevalent in individu

  • acanthosis nigricans orsak

    • Acanthosis nigricans: Who gets and causes

    Diseases & conditions
    Featured
    Atopic dermatitis: More FDA-approved treatments

    Research breakthroughs are giving patients with atopic dermatitis/eczema more ways to treat this condition. See what a treatment plan may include.

    Biosimilars: 14 FAQs

    Find answers to questions patients ask about this newer treatment option, including, “What’s involved in switching from a biologic to a biosimilar?”

    Everyday care
    Featured
    How to trim your nails

    Keep your nails looking their best with these tips from board-certified dermatologists.

    Relieve uncontrollably itchy skin

    Find out what may be causing the itch and what can bring relief.

    Darker Skin Tones
    Featured
    Fade dark spots

    Find out why dark spots appear and what can fade them.

    Untreatable razor bumps or acne?

    If you have what feels like razor bumps or acne on the back of your neck or scalp, you may have acne keloidalis nuchae. Find out what can help.

    Cosmetic treatments
    Featured
    Tattoo removal

    Find out why laser tattoo removal outshines other methods for removing a tattoo.

    Scar treatment

    If you want to diminish a noticeable scar, know these 10 things before having laser treatme

    Acanthosis nigricans

    Medical condition

    Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin.[1] It is usually found in body folds,[2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.[1]

    It is associated with endocrine dysfunction, especially insulin resistance and hyperinsulinaemia, as seen in diabetes mellitus. This activates the insulin-like growth factor receptors, which leads to proliferation of keratinocytes, fibroblasts and other cells in the skin. Activation of other growth factor receptors such as fibroblast growth factor receptors or epidermal growth factor receptor can also be responsible.[3]

    Signs and symptoms

    [edit]

    Acanthosis nigricans appears as dark brown-black, poorly defined, velvety patches of skin, typically affecting the face, neck, underarms, genitals, groin, elbows, knees, anus, umbilicus and nasal crease.[1]

    Causes

    [edit]

    It typically occurs in individuals younger than age 40, is associated with insulin resistance, type 2 diabetes, obesity or endocrinopathies, such a